Futures for the Dow Jones Industrials dumped 198 points, or 0.6%, to 34,162.
Futures for the S&P 500 fell 30.75 points, or 0.7%, to 4,371.25.
Futures for the NASDAQ Composite Index ditched 108 points, or 0.7%, to 13,999.75.
The blue-chip Dow is coming off a four-day winning streak, rising 4.7% for the week so far, and is also on pace for its biggest weekly gain since November 2020. The tech-heavy NASDAQ Composite is up 6% this week, headed for its best week since February 2021.
Shares of FedEx fell more than 3% in premarket trading after the U.S. delivery firm posted a lower-than-expected quarterly profit amid labor shortages, while the pandemic also hurt its holiday revenue growth.
GameStop saw its shares dropping about 7% in extended trading after the video game retailer reported an unexpected loss during the holiday quarter. The company said it will launch a new marketplace for non-fungible tokens, or NFTs, by the end of April.
Friday’s moves come as traders continued to digest the latest developments in the Ukraine-Russia war.
Several missiles hit an aircraft repair center on the outskirts Lviv in western Ukraine. Meanwhile, President Joe Biden is slated to speak with Chinese President Xi Jinping to discuss the conflict. A Ukrainian official also said one person was killed in an airstrike that hit Kyiv.
In Asia, the Nikkei 225 index gained 0.7%, while in Hong Kong, the Hang Seng index fell 0.4%.
Oil prices gained 41 cents to $103.39 U.S. a barrel.
Gold prices let go of three dollars to $1,944.20 U.S.